This study presents a novel procedure for optimizing a vibration control system composed of multiple U-shaped liquid containers, collectively referred to as the Multi-Sliding Tuned Liquid Column Damper (M-STLCD), aimed at reducing seismic responses in multi-story buildings. Each liquid container is equipped with a spring-dashpot mechanism that connects the unit to a floor of the main structure and allows controlled horizontal translation. The optimization procedure, structured as a sequence of iterations, installs and tunes one device at a time, while accounting for the effects of previously installed units. This enables the control strategy to progressively adapt to the evolving dynamic characteristics of the structure. For each STLCD unit, the procedure simultaneously determines the optimal installation floor and the structural vibration mode to be targeted. This is achieved by identifying the most effective placement along the building elevation while optimizing the damping ratio and natural frequency of the spring-dashpot mechanism, as well as the head-loss coefficient and the natural frequency associated with the liquid column. To demonstrate the effectiveness of the sequential optimization and placement procedure, the method is applied to different structures subjected to various types of excitation. Beyond validating the optimization framework, the performance of the M-STLCD is comprehensively evaluated in both time and frequency domains, and compared against optimized multi-unit configurations of traditional devices, namely, the Multi -Tuned Mass Damper (the M-TMD) and the Multi-Tuned Liquid Column Damper (the M-TLCD).