This paper presents the latest developments involving an innovative life-saving school desk, result of a multidisciplinary design process having as goal a limited increment of weight, dimensions, and costs as compared to conventional school desks, while significantly improving the capacity to resist static and dynamic load, as those that could be experienced in case of seismic damages. Specifically, this study illustrates: i) the structural concept behind the proposed school desks, ii) numerical analyses under exceptional loading conditions, and iii) the results of an experimental campaign in which the performances of full-scale prototypes were evaluated under static and dynamic (impact) loadings. The experimental outcomes were monitored using conventional contact sensors as well as computer-vision methodologies for displacement tracking of multiple-points.