Geotechnical monitoring represents a fundamental pillar in the strategy for mitigating seismic risk in road infrastructures, especially within a national context characterized by high seismicity and hydrogeological vulnerability. This contribution provides a critical overview of the technologies and methodologies employed in the geotechnical monitoring of infrastructure works. The study thoroughly examines both traditional and innovative measurement instruments, integrated monitoring systems, and automated data acquisition networks. Attention is also given to the role of satellite data and its integration with predictive models for assessing the stability of slopes and engineering structures, which are critical components of road networks in seismic areas. The analysis highlights how continuous monitoring, supported by advanced geotechnical analyses and early warning systems, can significantly reduce the risks associated with seismic events and allow for more efficient management of emergencies and intervention priorities. The synthesis of the analyzed approaches contributes to the development of operational guidelines for the implementation of effective monitoring systems, supporting resilience and sustainability policies for transportation infrastructures.