Precast construction employing modular 3D cells for housing was developed alongside frame and panel buildings since the end of WWII, mainly in Europe. This technology combined with in-situ concreting of wet joints was employed with a certain success up to around the ‘80s, after which it became progressively less popular due to the difficulties in handling transportation (both lifting and shipping due to the large cell dimensions) and limited benefits in construction due to the partial prefabrication, limiting its application in many countries to relatively small-size building components, such as kitchen/bathroom or service blocks. Thanks to the recent innovations of the precast concrete technology (both in production and structural connections), combined with the market evolution, this technology is nowadays experiencing a renovated interest for mid- and high-rise buildings, especially in Asia, where rapid dry or semi-dry assemblage of the cells allows for the full finishing of the units in factory, and for the full exploitation of the benefits induced by the prefabrication process. As a matter of fact, the structural behaviour of buildings employing this technology is currently lacking from assessment of their seismic performance. As a preliminary attempt to fill this gap, this paper presents the results of traditional seismic analysis with response spectrum carried out on a representative large residential building designed with 6, 12, 18 and 24 storeys modelled with shell elements and spring connections, analysing the limit PGAs associated to each typology and commenting the role of different connection devices and the possible design implications.